Cryptococcus gattii meningitis complicated by immune reconstitution inflammatory syndrome in an apparent immunocompetent host in Malaysia

Abstract

Cryptococcosis is a systemic fungal infection caused by <i>Cryptococcus neoformans</i> or <i>Cryptococcus gattii. Cryptococcus</i> causes a wide range of diseases, ranging from asymptomatic pulmonary lesions to disseminated disease involving the central nervous system, particularly meningoencephalitis. <i>C. gattii</i> infection has rarely been reported in Malaysia. We present a case of <i>C. gattii</i> meningitis with pulmonary cryptococcosis complicated by immune reconstitution inflammatory syndrome in an apparently immunocompetent person with no prior travel history.