Statistical Methods in Medical Research · 2021 · 26 citations · 29 references
ComputingBiostatisticsData ScienceMachine LearningStatistical LearningStatistical ModelingEnsemble LearningEnsemble MethodsFeature SelectionOverfittingPredictive Health ModelingVariable SelectionBoostingDistributional RegressionEarly StoppingExplanatory Variable SelectionGradient BoostingHigh-dimensional Variable SelectionMachine Learning Prediction ModelsOptimization For High-dimensional Data
We present a new procedure for enhanced variable selection for component-wise gradient boosting. Statistical boosting is a computational approach that emerged from machine learning, which allows to fit regression models in the presence of high-dimensional data. Furthermore, the algorithm can lead to data-driven variable selection. In practice, however, the final models typically tend to include too many variables in some situations. This occurs particularly for low-dimensional data ([Formula: see text]), where we observe a slow overfitting behavior of boosting. As a result, more variables get included into the final model without altering the prediction accuracy. Many of these false positives are incorporated with a small coefficient and therefore have a small impact, but lead to a larger model. We try to overcome this issue by giving the algorithm the chance to deselect base-learners with minor importance. We analyze the impact of the new approach on variable selection and prediction performance in comparison to alternative methods including boosting with earlier stopping as well as twin boosting. We illustrate our approach with data of an ongoing cohort study for chronic kidney disease patients, where the most influential predictors for the health-related quality of life measure are selected in a distributional regression approach based on beta regression.
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