Concepedia

The contribute of cerebrospinal fluid free light-chain assay in the diagnosis of multiple sclerosis and other neurological diseases in an Italian multicenter study

Gaetano Bernardi, Tiziana Biagioli, Paola Malpassi, Teresa De Michele, Domizia Vecchio, Anna Maria Repice, Alessandra Lugaresi, Massimiliano Mirabella, Valentina Torri Clerici, Ilaria Crespi

Multiple Sclerosis Journal · 2021 · 19 citations · 25 references

DOI

Abstract

Our findings support the diagnostic utility of FLC indices in MS and other CNS inflammatory disorders, suggesting a combined use of FLC and OCB to help clinicians with complementary information.

References

25

Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis

Charlotte E. Teunissen, Til Menge, Ayşe Altıntaş et al. · Multiple Sclerosis Journal · 2013 · 162 citations

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Elevated levels of kappa free light chains in CSF support the diagnosis of multiple sclerosis

Stefan Presslauer, Dejan Milosavljevic, Thomas Brücke et al. · Journal of Neurology · 2008 · 142 citations

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Kappa free light chains is a valid tool in the diagnostics of MS: A large multicenter study

CE Leurs, HAM Twaalfhoven, Birgit I. Lissenberg‐Witte et al. · Multiple Sclerosis Journal · 2019 · 94 citations · Full text

Kappa Free Light Chains in Cerebrospinal Fluid as Markers of Intrathecal Immunoglobulin Synthesis

Christian Fischer, Borros Arneth, Jürgen Koehler et al. · Clinical Chemistry · 2004 · 64 citations · Full text

High levels of cerebrospinal fluid free kappa chains predict conversion to multiple sclerosis

Luisa María Villar, Mercedes Espiño, Lucienne Costa‐Frossard et al. · Clinica Chimica Acta · 2012 · 62 citations

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