A phase II randomized trial to evaluate the long-term (12-week) efficacy and safety of OC-01 (varenicline solution) nasal spray for dry eye disease: The MYSTIC study

Hugo Quiroz-Mercado, Everardo Hernández-Quíntela, Kuei Hsun Chiu, Eugenia Henry, Jeffrey Nau

The Ocular Surface · 2021 · 44 citations · 19 references

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Abstract

OC-01 (varenicline solution) nasal spray improved tear production in patients with dry eye disease over a long-term (12-week) period, and represents a receptor neuro-activator with a nasal route of administration that spares the ocular surface to stimulate tear production.

References

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