Concepedia

Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy

Jonas Bochem, Henning Zelba, Janine Spreuer, Teresa Amaral, Nikolaus B. Wagner, Oltin T. Pop, Karolin Thiel, Can Yurttas, Daniel Soffel, Stephan Forchhammer,

Journal for ImmunoTherapy of Cancer · 2021 · 15 citations · 32 references

DOIFull text

Open access

Abstract

Our findings suggest a PD-1 blockade-dependent infiltration of melanoma-reactive T cells from the periphery into the tumor and imply that this seminally contributes to effective treatment.

References

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