Clinical Case Reports · 2021 · 10 citations · 25 references
MedicineHematologyPharmacotherapyPulmonologyStem Cell TransplantationTransplant PharmacotherapyAcute Lung InjuryHematopoietic Stem Cell Transplant PharmacotherapyMyelodysplastic SyndromesPneumonia PharmacotherapyPost-transplant ComplicationsTransplant ComplicationsAcute Lung Injury PathophysiologyHematopoietic Stem Cell Transplant ComplicationsHematopoietic Stem Cell Transplantation ImmunotherapyMyelodysplastic Syndrome TherapyMyelodysplastic Syndrome TreatmentPulmonary Complications After TransplantationRefractory Myelodysplastic SyndromeSevere Pneumonia Management
Idiopathic pneumonia syndrome (IPS) is an acute lung complication observed after the early posthematopoietic stem cell transplantation (HSCT) period. Ruxolitinib was effective for a patient with myelodysplastic syndrome who developed severe IPS after second HSCT. No severe adverse effects were observed. Ruxolitinib may be an alternative choice for HSCT-related IPS.
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