A comparison of the anticonvulsant effects of competitive and non-competitive antagonist of the N-methyl-d-aspartate receptor

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

Erik H.F. Wong, J A Kemp, Tony Priestley et al. · Proceedings of the National Academy of Sciences · 1986 · 1.8K citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

Anticonvulsant Action of Excitatory Amino Acid Antagonists

M. J. Croucher, J.F. Collins, B.S. Meldrum · Science · 1982 · 693 citations

Medicine, Neuroscience, Pharmacology +16

Non-competitive antagonists of excitatory amino acid receptors

John A. Kemp, Alan C. Foster, Erik H.F. Wong · Trends in Neurosciences · 1987 · 499 citations

Life Sciences, Neuroscience, Pharmacology +14

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

Bradley V. Clineschmidt, Gregory E. Martin, Patricia R. Bunting · Drug Development Research · 1982 · 498 citations

Medicine, Neurology, Pharmacology +12

CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]d-AP5 binding sites on brain membranes and anticonvulsant activity

J. Davies, Richard H. Evans, Paul L. Herrling et al. · Brain Research · 1986 · 310 citations

Life Sciences, Neuroscience, Pharmacology +13