Transdermal drug transport and metabolism. I. Comparison of in vitro and in vivo results.

Skin penetration and metabolism of topically applied chemicals in six mammalian species, including man: An in vitro study with benzo6a9pyrene and testosterone*1

John Y. Kao · Toxicology and Applied Pharmacology · 1985 · 168 citations

Pharmacy, Pharmacology, Toxicology +14

Quantitation of cutaneous toxicity: An in vitro approach using skin organ culture

John Y. Kao, Jerry W. Hall, James M. Holland · Toxicology and Applied Pharmacology · 1983 · 66 citations

Pharmacy, Dermatology, Toxicology +13

A multisample apparatus for kinetic evaluation of skin penetration in vitro: The influence of viability and metabolic status of the skin

James M. Holland, John Y. Kao, M.J. Whitaker · Toxicology and Applied Pharmacology · 1984 · 66 citations

Pharmacy, Bioengineering, Biomedical Engineering +14

Skin structure and metabolism: relevance to the design of cutaneous therapeutics.

Daniel A. W. Bucks · Pharmaceutical Research · 1984 · 61 citations

Pharmacy, Biochemistry, Dermatology +14

Skin absorption and cutaneous first pass metabolism of topical steroids: in vitro studies with mouse skin in organ culture.

John Y. Kao, Jerry W. Hall · Journal of Pharmacology and Experimental Therapeutics · 1987 · 41 citations

Life Sciences, Pharmacokinetics, Pharmacology +16