PubMed · 2007 · 88 citations · 41 references
EngineeringRoot Canal TherapySurgeryEnvironmental ChemistryChemical SafetyCorrosionSodium Hypochlorite AccidentsToxicologySodium HypochloriteChemical HazardPoisoningEcotoxicologyNaocl AccidentsRoot Canal TreatmentEnvironmental EngineeringForensic ToxicologyEnvironmental ToxicologyMedicineAnesthesiology
Sodium hypochlorite (NaOCl) in various concentrations is the most widely used endodontic irrigant, but it can be an irritant to vital tissues. There are several reports about the complications of irrigation with NaOCl during root canal therapy. Most of the complications are the result of accidental extrusion of the solution from the apical foramen or accessory canals or perforations into the periapical area. This article is a review and comparison of all reported NaOCl accidents in the literature.
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Brenda Paula Figueiredo de Almeida Gomes, Caio Cézar Randi Ferraz, M. E. Vianna et al. · International Endodontic Journal · 2001 · 490 citations
Cytotoxic effects of NaOCl on vital tissue
E.L. Pashley, N.L. Birdsong, KARL M. BOWMAN et al. · Journal of Endodontics · 1985 · 310 citations