Molecular Genetic Changes in a Series of Neuroepithelial Tumors of Childhood

Overexpression of the EGF Receptor and <i>p53</i> Mutations are Mutually Exclusive in the Evolution of Primary and Secondary Glioblastomas

Kunihiko Watanabe, Osamu Tachibana, Kazufumi Sato et al. · Brain Pathology · 1996 · 734 citations · Full text

Medicine, Genetics, Oncology +17

PTEN Mutation, EGFR Amplification, and Outcome in Patients With Anaplastic Astrocytoma and Glioblastoma Multiforme

Justin S. Smith, Issei Tachibana, Sandra Passe et al. · JNCI Journal of the National Cancer Institute · 2001 · 645 citations

Medicine, Molecular Genetics, Oncology +17

Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails.

A. Jonas Ekstrand, Noriaki Sugawa, C. David James et al. · Proceedings of the National Academy of Sciences · 1992 · 607 citations

Medicine, Molecular Genetics, Oncology +10

Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors.

Fleming Tp, Abha Saxena, Clark Wc et al. · PubMed · 1992 · 384 citations

Medicine, Molecular Biology, Oncology +16

p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma.

Andreas von Deimling, Robert H. Eibl, Hiroko Ohgaki et al. · PubMed · 1992 · 296 citations

Life Sciences, Genetics, Molecular Genetics +15