Nephrotic Syndrome as a Complication of Immune Tolerance in Hemophilia B

Bruce M. Ewenstein, C. Takemoto, Indira Warrier, Jeanne M. Lusher, P. Saidi, Joan Eisele, Lawrence J. Ettinger, Donna DiMichele

Blood · 1997 · 134 citations · 5 references

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Abstract

To the Editor: Inhibitors to factor IX (fIX) develop in approximately 1.5% to 3% of persons with severe hemophilia B and are commonly associated with the complete absence of fIX antigen due to large gene deletions or nonsense mutations.[1][1] The occurrence of high-titer inhibitors severely

References

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