Journal of the American Veterinary Medical Association · 1980 · 55 citations · 0 references
Veterinary MedicineImmunologyInfectious DiseasesAdaptive ImmunityImmunology Of Infectious DiseasesSwine MedicineLivestock Infectious DiseasesSwine DiseaseSwine HealthSwine ImmunologySwine Infectious DiseasesSwine PathologyBacterial Immunity In SwineInoculationPorcine Adaptive ImmunityPorcine Infectious DiseasesSwine Immune ResponseSwine Immune-mediated DiseaseSwine ImmunopathologyViable Cell Count
The immune status of 29 pigs recovered from swine dysentery (SD) was evaluated after reexposure to Treponema hyodysenteriae. Pigs which had recovered from SD and remained asymptomatic for 4 to 6, 9 to 13, and 16 to 17 weeks after initial inoculation were reexposed to 1.5 X 10(9) viable cells of T hyodysenteriae per pig. Pigs which had recovered from SD were not shedding T hyodysenteriae, as determined by selective cultural examination of feces, before they were reexposed. Of 29 pigs reexposed to T hyodysenteriae, 27 were resistant to SD. In contrast, 23 of 28 control pigs developed signs of SD when exposed to T hyodysenteriae for the first time. Significant differences in immunity were not observed between pigs from the three convalescent periods. Serum agglutinins to T hyodysenteriae were present in recovered pigs for approximately 8 weeks after inoculation.