Concepedia

SUSTAINED SPINAL CORD COMPRESSION

Gregory D. Carlson, Carey Gorden, Shigenobu Nakazawa, Eiji Wada, Jeremy Smith, Joseph C. LaManna

Journal of Bone and Joint Surgery · 2003 · 41 citations · 19 references

DOI

Abstract

The methylprednisolone administered in this study did not provide a large or significant lasting benefit with regard to neurological preservation or restoration. Methylprednisolone may reduce regional spinal cord blood flow through mechanisms affecting normal autoregulatory blood-flow function.

References

19

A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

Michael B. Bracken, M J Shepard, William F. Collins et al. · New England Journal of Medicine · 1990 · 2.7K citations · Full text

Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study

Michael B. Bracken · JAMA · 1997 · 1.2K citations

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Administration of Methylprednisolone for 24 or 48 Hours or Tirilazad Mesylate for 48 Hours in the Treatment of Acute Spinal Cord Injury

Michael B. Bracken · JAMA · 1997 · 1.2K citations

, , +17

Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up

M B Bracken, M J Shepard, Theodore R. Holford et al. · Journal of neurosurgery · 1998 · 532 citations

Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2

Michael B. Bracken, Theodore R. Holford · Journal of neurosurgery · 1993 · 331 citations