Concepedia

Effect of topically applied anti-CD4 monoclonal antibodies on orthotopic corneal allografts in a rat model.

Uwe Pleyer, Jessica K. Milani, Andres J Dukes, Joseph Chou, Sabine Lutz, Dieter Rückert, Heinz‐Jürgen Thiel, Bartly J. Mondino

PubMed · 1995 · 57 citations · 6 references

Abstract

The results suggest that treatment with topically applied LIP-anti-CD4 mAb prolongs graft survival in orthotopic corneal grafts in a rat model. The beneficial effect of LIP-anti-CD4 mAb, probably due to enhanced intraocular delivery, was achieved by using relatively low doses of mAb.

References

6

Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen

Denise Gay, Paul J. Maddon, Rafick‐Pierre Sékaly et al. · Nature · 1987 · 348 citations · Full text

, , +11

Experimental allergic encephalomyelitis: successful treatment <i>in vivo</i> with a monoclonal antibody that recognizes T helper cells.

Steven W. Brostoff, Donald W. Mason · The Journal of Immunology · 1984 · 222 citations

Prolongation of Corneal Allograft Survival with Liposome-encapsulated Cyclosporine in the Rat Eye

Jessica K. Milani, Uwe Pleyer, Andres J Dukes et al. · Ophthalmology · 1993 · 65 citations

, , +8

OKT4 AND OKT4A ANTIBODY TREATMENT AS IMMUNOSUPPRESSION FOR KIDNEY TRANSPLANTATION IN RHESUS MONKEYS

Margreet Jonker, P. Neuhaus, C. Zurcher et al. · Transplantation · 1985 · 54 citations

Assessment of ocular irritability of liposome preparations. .

Kadzuya TANIGUCHI, Yukio Yamamoto, K Itakura et al. · Journal of Pharmacobio-Dynamics · 1988 · 45 citations · Full text

, , +10