Syntheses of Amino Alcohols and Chiral C 2 -Symmetric Bisoxazolines Derived from O -Alkylated R -4-Hydroxyphenylglycine and S -Tyrosine

Abstract

Chiral C-2-symmetric bisoxazolines 1b-f and 2b,c, derived from 4'-O-alkylated R-4-hydroxy-phenylglycine or S-tyrosine, were prepared. As intermediates, a series of chiral amino alcohols possessing substituted phenolic groups was prepared and fully characterized.