Lower Helicobacter pylori infection and peptic ulcer disease prevalence in patients with AIDS and suppressed CD4 counts.

Abstract

The prevalence of HP in HIV-positive patients with a CD4 count less than 200 is significantly lower (p < 0.001) than that found in HIV-negative patients. The number of peptic ulcers in the HIV-positive group with CD4 < 200 was significantly less (p = 0.035) than that of the HIV-negative patients. These results suggest a role of CD4 cell and immune function in sustaining HP infection and HP-related peptic ulcer disease.