Methemoglobinemia and Hemolytic Anemia After Phenazopyridine Hydrochloride (Pyridium) Administration in End-Stage Renal Disease

Abstract

Phenazopyridine is a commonly used urinary tract analgesic. As illustrated by the case we have reported, its use may be complicated by the development of methemoglobinemia and hemolytic anemia, especially in patients with renal insufficiency.