American Journal of Psychiatry · 1977 · 26 citations · 2 references
Public HealthPreventive MedicineBehavioral PharmacologySubstance Use DisordersTobacco ControlNicotine AddictionNicotine DependenceSmoking CessationTobacco DependenceTobacco UseTobacco Use CessationChewing Gum UseNicotine CravingNicotine Gum TherapyNicotine Withdrawal SyndromePharmacotherapy For Nicotine DependencePharmacotherapy For Tobacco DependenceRelapse ProcessesWithdrawal Symptoms
The authors present three case studies which suggest that smoking withdrawal symptoms in certain individuals may be due to removal of nicotine per se, implying that smokers may develop a true physical dependence on cigarettes. Nicotine replacement by use of an experimental chewing gum containing nicotine in various dosages successfully prevented or alleviated the abstinence symptoms of the subjects studied.
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Nicotine-containing chewing gum as an anti-smoking aid
B. Brantmark, P. Ohlin, H. Westling · Psychopharmacology · 1973 · 71 citations