PubMed · 2009 · 30 citations · 0 references
MedicineNeurologyPharmacotherapyNeuropharmacologyNeuropsychiatryPsychopharmacologyAntidepressant TherapyAntipsychotic PharmacologyAntiretroviral TherapyHuman Immunodeficiency Virus PharmacotherapySerotonergic PharmacologySerotonergic SignalingClinical SymptomsHiv-associated NeuropathologyMirtazapine TherapyProgressive Multifocal Leukoencephalopathy Imaging
We describe the clinical course of an HIV-infected patient with progressive multifocal leukoencephalopathy who took mirtazapine for his depression. After six months of therapy the clinical symptoms had not worsened and the neuroradiological image of the brain was unchanged. Further studies are necessary to determine the effect of serotonin receptor antagonist in treating PML associated to HIV.