Regulation of tumor necrosis factor alpha and its specific receptors during Toxoplasma gondii infection in human monocytic cells

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-α

Ricardo T. Gazzinelli, Maria Wysocka, Sara Hieny et al. · The Journal of Immunology · 1996 · 929 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity

Hartmut Engelmann, Dan Aderka, Menachem Rubinstein et al. · Journal of Biological Chemistry · 1989 · 441 citations · Full text

Life Sciences, Biochemistry, Immunology +13

Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha

C.A. Hunter, Carlos S. Subauste, Victor H. Van Cleave et al. · Infection and Immunity · 1994 · 372 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF- <i>alpha</i> and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation.

Ricardo T. Gazzinelli, Isam A. Eltoum, Thomas A. Wynn et al. · The Journal of Immunology · 1993 · 350 citations

Veterinary Medicine, Immunology, Infectious Diseases +15

Tumor necrosis factor-alpha triggers antitoxoplasmal activity of IFN-gamma primed macrophages

L. David Sibley, Linda B. Adams, Yoshiki Fukutomi et al. · The Journal of Immunology · 1991 · 190 citations · Full text

Life Sciences, Immunology, Infectious Diseases +15