Concepedia

Interleukin-25 and Interleukin-33 as Mediators of Eosinophilic Inflammation in Chronic Rhinosinusitis

Matthew Lam, Laura Hull, Andrew Imrie, Kornkiat Snidvongs, David Chao‐Wu Chin, Ellie Pratt, Larry Kalish, Raymond Sacks, Peter Earls, William A. Sewell,

American Journal of Rhinology and Allergy · 2015 · 75 citations · 25 references

DOI

Abstract

IL-25 and IL-33 overexpression was observed in eosinophilic CRS, The release of these cytokines by dysfunctional endothelium may perpetuate the eosinophillic inflammation in CRS.

References

25

European Position Paper on Rhinosinusitis and Nasal Polyps 2020

W.J. Fokkens, Valerie J. Lund, C. Hopkins et al. · Rhinology Journal · 2020 · 5.4K citations · Full text

EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists

W. J. Fokkens, Valerie J. Lund, J Mullol et al. · Rhinology Journal · 2012 · 2.4K citations

Asthma, Nasal Polyps, Otorhinolaryngology +17

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

Daniel R. Neill, See Heng Wong, Agustin Bellosi et al. · Nature · 2010 · 2K citations · Full text

Inflammation, Type-2 Immunity, Immune Cell Development +8

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

Kazuyo Moro, Taketo Yamada, M. Tanabe et al. · Nature · 2009 · 1.9K citations

Inflammation, Metabolic Syndrome, Cytokine +11

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

Jenny Mjösberg, Sara Trifari, Natasha K. Crellin et al. · Nature Immunology · 2011 · 1.1K citations · Full text