Substrate specificity of the dsRNA unwinding/modifying activity.

DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

James L. Manley, Andrew Fire, Amparo Cano et al. · Proceedings of the National Academy of Sciences · 1980 · 1.3K citations

Viral Replication, Medicine, Viral Polymerase Mechanism +15

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

Michael H. Malim, Joachim Hauber, Shu‐Yun Le et al. · Nature · 1989 · 1.3K citations

Structured Target Sequence, Nuclear Export, Viral Replication +12

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

Mark J. Zoller, Michael J. Smith · Methods in enzymology on CD-ROM/Methods in enzymology · 1983 · 1.1K citations

Nucleic Acid Chemistry, Genetics, Oligonucleotide +7

An unwinding activity that covalently modifies its double-stranded RNA substrate

Brenda Bass, Harold Weintraub · Cell · 1988 · 728 citations

Chromatin, Transcriptional Regulation, Natural Sciences +13

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

Mark A. Muesing · Cell · 1987 · 662 citations

Mrna Accumulation, Viral Replication, Human Retrovirus +9