PubMed · 1996 · 21 citations · 0 references
Natural SciencesBiophysicsPhysiologyAgingBiomedical OpticsBiophotonicsAging PhysiologyCardiovascular AgingCerebrovascular PhysiologyFluorescence ImagingFluorescence MicroscopyTissue Optical PropertiesAge-dependent ProcessesAge-related Tissue Optical PropertiesAge-related Vascular ChangesAging-related Vascular ChangesDecay TimeDecay Time AnalysisFluorescence Decay AnalysisTime-resolved Fluorescence Imaging
Human arteries fluoresce as a result of illumination by UV-light. The fluorescence characteristics of the human aorta and basilar artery were investigated with respect to aging. For this experiment, a time-resolved microscope fluorometer was employed. Resultant fluorescence decayed on a nanosecond scale when applying pulse UV-light. These fluorescences were found to be age dependent in the basilar artery; the fluorescence decay time decreased with increasing human age. However, fluorescence from the aorta did not show the age dependency.