Wegener's granulomatosis in a patient with Crohn's disease.

Abstract

Wegener's granulomatosis and Crohn's disease are two distinct chronic inflammatory diseases that may involve various organ systems, including the alimentary tract and the oropharynx. In both diseases there is an association with different types of anti-neutrophil cytoplasmic antibodies. We describe a patient previously diagnosed with Crohn’s disease, presenting 13 years later with a perforated nasal septum and histological evidence of nasal granulomas and ultimately diagnosed as having Wegener’s granulomatosis.