Copper metabolism in mottled mouse mutants. Defective placental transfer of 64Cu to foetal brindled (<i>Mo</i> <i>br</i>) mice

Abstract

Decreased placental transfer of 64Cu into both Mobr/Y and Mobr/+ foetuses was apparent after its administration to pregnant Mobr/+ mice. The severity of impairment and the degree of retention and accumulation of 64Cu in the placenta was not as great as has been previously observed in the gut of the suckling Mobr/Y mice.