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Sub-lingual administration of a polyvalent mechanical bacterial lysate (PMBL) in patients with moderate, severe, or very severe chronic obstructive pulmonary disease (COPD) according to the GOLD spirometric classification: A multicentre, double-blind, randomised, controlled, phase IV study (AIACE study: Advanced Immunological Approach in COPD Exacerbation)

Advanced Lung DiseaseSub-lingual AdministrationGold Spirometric ClassificationMedicineCopd ExacerbationClinical MicrobiologyPulmonary Disease