Astrogliosis and compensatory neurogenesis after the first ethanol binge drinking‐like exposure in the adolescent rat

Abstract

Our findings demonstrate that the cognitive deficits associated with hippocampal synaptic plasticity alterations that we previously characterized 48 h after the first binge-like ethanol exposures are associated with hippocampal structural plasticity, astrogliosis, and decreased neuronal TLR4 expression, but not with microglia reactivity.