Publication | Closed Access
Stem Cell‐Recruiting Injectable Microgels for Repairing Osteoarthritis (Adv. Funct. Mater. 48/2021)
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2021
Year
Tissue EngineeringEngineeringBiomimetic MaterialsInjectable Porous MicrogelBiomaterials DesignBiofabricationPromising Therapeutic EffectBiomedical EngineeringOrthopaedic SurgeryRegenerative MedicineRegenerative BiomaterialsCartilage DegenerationOsteoarthritisTranslational Tissue EngineeringMatrix BiologyRegenerative EngineeringMusculoskeletal Regenerative EngineeringStem Cell TherapiesFunctional Tissue EngineeringMesenchymal Stem CellInjectable MicrogelsStem Cell EngineeringStem-cell TherapyMedicineBiomaterialsBiocompatible Material
Injectable Microgels Inspired by the phenomenon where islands could recruit seabirds for nesting, in article number 2105084, Xiaoji Luo, Wenguo Cui, Wei Huang, and co-workers present an injectable porous microgel generated via microfluidic technology that is non-covalently loaded with PDGF-BB and TGF-β3, forming “cell island” microgels that can serve as a temporary “nest site” to recruit endogenous stem cells and presents a promising therapeutic effect for osteoarthritic cartilage damage.