Peripheral innate and adaptive immune cells during <scp>COVID</scp> ‐19: Functional neutrophils, pro‐inflammatory monocytes, and half‐dead lymphocytes

Abstract

We suggest that SARS-CoV-2 primarily affects the lymphocytes and not the innate cells. The increased baseline activation of Caspase-3 could make the COVID-19 lymphocytes more vulnerable to cell death. Therefore, this may interrupt the crosstalk between the adaptive and innate immune systems.