AMPK inhibitor BML-275 induces neuroprotection through decreasing cyt c and AIF expression after transient brain ischemia

Reversible middle cerebral artery occlusion without craniectomy in rats.

Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke · 1989 · 7.4K citations · Full text

Mca Occlusion, Cerebral Vascular Regulation, Neurovascular Disease +18

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.2K citations · Full text

Protein Function, Signal Transduction, Biochemistry +12

Molecular characterization of mitochondrial apoptosis-inducing factor

Santos A. Susín, Hans Kristian Lorenzo, Naoufal Zamzami et al. · Nature · 1999 · 4K citations

Biochemistry, Mitochondrial Function, Cell Death +4

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

Luc Pellerin, Pierre J. Magistretti · Proceedings of the National Academy of Sciences · 1994 · 2.8K citations · Full text

Biochemistry, Neurophysiology, Medicine +15

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

Paul B. Yu, Charles C. Hong, Chetana Sachidanandan et al. · Nature Chemical Biology · 2007 · 1K citations · Full text

Developmental Biology, Iron Metabolism, Physiology +8