Urine Proteomics and Renal <scp>Single‐Cell</scp> Transcriptomics Implicate Interleukin‐16 in Lupus Nephritis

Abstract

Urine proteomics may profoundly change the diagnosis and management of LN by noninvasively monitoring active intrarenal biologic pathways. These findings implicate IL-16 in LN pathogenesis, designating it as a potentially treatable target and biomarker.