Concepedia

Publication | Open Access

The dietary fibre rhamnogalacturonan improves intestinal epithelial barrier function in a microbiota‐independent manner

DOIFull Paper Access

20

Citations

34

References

2021

Year

Cristiane Hatsuko Baggio, Judie Shang, Marilyn Gordon, Matthew Stephens, P Y von der Weid, Adamara Machado Nascimento, Yony Román-Ochoa, Thales R. Cipriani, Wallace K. MacNaughton
British Journal of Pharmacology

Abstract

RGal enhances intestinal epithelial barrier function through activation of TLR4 and PKC signalling pathways. Elucidation of RGal mechanisms of action could lead to new, dietary approaches to enhance mucosal healing in inflammatory bowel diseases.

References

YearCitations

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