Association of IL‐1<i>β</i>, NLRP3, and COX‐2 Gene Polymorphisms with Autoimmune Thyroid Disease Risk and Clinical Features in the Iranian Population

Abstract

The results manifest the significant impact of IL-1<i>β</i> rs1143634 and COX-2 (rs2745557) SNPs and HT development and IL-1<i>β</i> rs1143634 SNP on GD occurrence risk. Furthermore, a significant relationship was observed between some clinical features of HT and GD groups and studied SNPs.