APL Photonics · 2021 · 12 citations · 24 references
Tissue EngineeringEngineeringBiomimetic MaterialsBiomaterials DesignUniform HfsBiofabricationBiomedical EngineeringFiber OpticsProjection-suspended StereolithographyHydrogelsDigital FabricationProjection-suspended Stereolithography 3DBiomedical DevicesHydrogel FibersFabrication TechniqueBiophotonics3D BioprintingOptical Sensors3D PrintingBiopolymer GelMicrofabricationBiomedical DiagnosticsBiomaterials
Hydrogel fibers (HFs) have shown great potential for delivering light and sensing in vivo. However, HFs commonly suffer from high optical attenuation, which significantly affects their light-guiding efficiency and sensing performance. Here, we demonstrate a projection-suspended stereolithography (PSS) 3D printing method for fabricating low-loss HFs. Axially continuous and uniform HFs are produced via a light-curing area that floats on the precursor solution. Additionally, PSS improves the guiding efficiency of the HF by simultaneously regulating the fiber diameter, core–cladding structure, and refractive index. We obtained a loss of ≤0.15 dB/cm, which is better than that reported by previous studies. We also demonstrate that the fabricated HF provides light delivery and sensing capability in deep tissues, which will benefit the development of biomedicine and optogenetics. The PSS method heralds a novel fabrication for advanced waveguides.
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