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Similarities and differences upon binding of naturally occurring Δ9-tetrahydrocannabinol-derivatives to cannabinoid CB1 and CB2 receptors

Iu Raïch, Rafael Rivas‐Santisteban, Alejandro Lillo, Jaume Lillo, Irene Reyes‐Resina, Xavier Nadal, Carlos Ferreiro‐Vera, Verónica Sánchez de Medina, María Majellaro, Eddy Sotelo,

Pharmacological Research · 2021 · 31 citations · 63 references

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References

63

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

Yehiel Gaoni, Raphael Mechoulam · Journal of the American Chemical Society · 1964 · 2.4K citations

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Cannabidiol is a negative allosteric modulator of the cannabinoid CB <sub>1</sub> receptor

Robert B. Laprairie, Amina M. Bagher, Michael E. Kelly et al. · British Journal of Pharmacology · 2015 · 960 citations · Full text

Cannabidiol displays unexpectedly high potency as an antagonist of CB<sub>1</sub>and CB<sub>2</sub>receptor agonists<i>in vitro</i>

Adèle Thomas, Gemma L. Baillie, Angela M. Phillips et al. · British Journal of Pharmacology · 2007 · 739 citations · Full text

Crystal Structure of the Human Cannabinoid Receptor CB1

Tian Hua, Kiran Vemuri, Mengchen Pu et al. · Cell · 2016 · 662 citations · Full text

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RETRACTED ARTICLE: Crystal structures of agonist-bound human cannabinoid receptor CB1

Tian Hua, Kiran Vemuri, Spyros P. Nikas et al. · Nature · 2017 · 500 citations · Full text