<i>Fusobacterium nucleatum </i>colonization is associated with decreased survival of <i>helicobacter pylori</i>-positive gastric cancer patients

Abstract

<i>F. nucleatum</i> colonization leads to deregulation of actin dynamics and likely changes cancer cell mobility. Cohort analysis demonstrated that <i>F. nucleatum</i> colonization leads to poorer prognosis in <i>H. pylori-</i>positive patients with late-stage gastric cancer. Hence, combined colonization of <i>F. nucleatum</i> and <i>H. pylori</i> is a predictive biomarker for poorer survival in late-stage gastric cancer patients treated with gastrectomy.