A transcriptional signature detects homologous recombination deficiency in pancreatic cancer at the individual level

Regularization Paths for Generalized Linear Models via Coordinate Descent

Jerome H. Friedman, Trevor Hastie, Robert Tibshirani · Journal of Statistical Software · 2010 · 16.3K citations · Full text

Engineering, Machine Learning, Regularization Path +11

Regularization Paths for Generalized Linear Models via Coordinate Descent.

Jerome H. Friedman, Trevor Hastie, Rob Tibshirani · PubMed · 2010 · 14K citations

Engineering, Machine Learning, High-dimensional Method +10

Inferring tumour purity and stromal and immune cell admixture from expression data

Kosuke Yoshihara, Maria Shahmoradgoli, Emmanuel Martínez et al. · Nature Communications · 2013 · 10.4K citations · Full text

Signatures of mutational processes in human cancer

Nature · 2013 · 9.9K citations · Full text

Somatic Variant, Tumor Heterogeneity, Mutational Processes +6

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

Matthew D. Wilkerson, D. Neil Hayes · Bioinformatics · 2010 · 6K citations · Full text