Tanshinone IIA derivatives induced S-phase arrest through stabilizing c-myc G-quadruplex DNA to regulate ROS-mediated PI3K/Akt/mTOR pathway

Cancer Statistics, 2021

Rebecca L. Siegel, Kimberly D. Miller, Hannah E. Fuchs et al. · CA A Cancer Journal for Clinicians · 2021 · 17.4K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: relevance for NK–T cell interaction

Michele Ardolino, Alessandra Zingoni, Cristina Cerboni et al. · Blood · 2011 · 140 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

The antitumor effect of tanshinone IIA on anti-proliferation and decreasing VEGF/VEGFR2 expression on the human non-small cell lung cancer A549 cell line

Jun Xie, Jiahui Liu, Heng Liu et al. · Acta Pharmaceutica Sinica B · 2015 · 113 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Id-1 activation of PI3K/Akt/NF B signaling pathway and its significance in promoting survival of esophageal cancer cells

B. Li, Peter Y. K. Cheung, Xia Wang et al. · Carcinogenesis · 2007 · 102 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Tanshinone IIA inhibits viral oncogene expression leading to apoptosis and inhibition of cervical cancer

Radha Munagala, Farrukh Aqil, Jeyaprakash Jeyabalan et al. · Cancer Letters · 2014 · 95 citations

Medicine, Oncology, Pharmacology +14