Detection of PKD1 and PKD2 Somatic Variants in Autosomal Dominant Polycystic Kidney Cyst Epithelial Cells by Whole-Genome Sequencing - Concepedia

Concepedia

Publication | Open Access

Detection of PKD1 and PKD2 Somatic Variants in Autosomal Dominant Polycystic Kidney Cyst Epithelial Cells by Whole-Genome Sequencing

DOI Full Paper Access

33

Citations

40

References

2021

Year

Zhengmao Zhang, Hanwen Bai, Jon D. Blumenfeld, Andrew Ramnauth, Irina Barash, Martin R. Prince, Adrian Y. Tan, Alber Michaeel, Genyan Liu, Ines Chicos,

Journal of the American Society of Nephrology

Abstract

These findings further support a cellular recessive mechanism for cystogenesis in ADPKD primarily caused by inactivating germline and somatic variants of PKD1 or PKD2 genes in kidney cyst epithelium.

References

	Year	Citations

Page 1