Concepedia

Oral vaccination with recombinant Lactobacillus plantarum encoding Trichinella spiralis inorganic pyrophosphatase elicited a protective immunity in BALB/c mice

Hu Chen, Yang Xu, Hui Hao, Ruo Dan Liu, Peng Jiang, Shao Rong Long, Zhong Quan Wang, Jing Cui

PLoS neglected tropical diseases · 2021 · 51 citations · 52 references

DOIFull text

Open access

Abstract

TsPPase plays a crucial role in T. spiralis molting and development, oral vaccination with rTsPPase induced a significant local mucosal sIgA response and systemic Th1/Th2 immune response, and immune protection against T. spiralis infection in BALB/c mice.

References

52

Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease.

Parris M. Kidd · PubMed · 2003 · 1.1K citations

, , +18

Progress in Bacillus subtilis Spore Surface Display Technology towards Environment, Vaccine Development, and Biocatalysis

Huayou Chen, Jawad Ullah, Jinru Jia · Microbial Physiology · 2017 · 357 citations · Full text

Characterization of a Trichinella spiralis putative serine protease. Study of its potential as sero-diagnostic tool

Ge Sun, Yan Song, Peng Jiang et al. · PLoS neglected tropical diseases · 2018 · 125 citations · Full text

Comparative proteomic analysis of surface proteins of Trichinella spiralis muscle larvae and intestinal infective larvae

Ruo Dan Liu, Jing Cui, Xiao Lin Liu et al. · Acta Tropica · 2015 · 124 citations

, , +9

Early serodiagnosis of trichinellosis by ELISA using excretory–secretory antigens of Trichinella spiralis adult worms

Ge-Ge Sun, Zhong-Quan Wang, Chunying Liu et al. · Parasites & Vectors · 2015 · 113 citations · Full text