Comparison of the different protocols of the Hen's Egg Test-Chorioallantoic Membrane (HET-CAM) by evaluating the eye irritation potential of surfactants

Hen's egg chorioallantoic membrane test for irritation potential

N.-P. Luepke · Food and Chemical Toxicology · 1985 · 472 citations

Pharmacy, Toxicology, Reproductive Toxicology +2

The HET-CAM test: An alternative to the draize eye test

N.-P. Luepke, F. H. Kemper · Food and Chemical Toxicology · 1986 · 169 citations

Health Professions, Ophthalmology, Optometry +10

The HET–CAM, a Useful In Vitro Assay for Assessing the Eye Irritation Properties of Cosmetic Formulations and Ingredients

W. Steiling, Marguerite Bracher, Pascal Courtellemont et al. · Toxicology in Vitro · 1999 · 147 citations

Pharmacy, Pharmaceutics, Toxicology +11

Analysis of Draize eye irritation testing and its prediction by mining publicly available 2008-2014 REACH data

Thomas Luechtefeld · ALTEX · 2016 · 116 citations · Full text

Pharmacy, Ophthalmology, Toxicology +13

Validation study of alternatives to the Draize eye irritation test in Germany: Cytotoxicity testing and HET-CAM test with 136 industrial chemicals

Horst Spielmann, S. Kalweit, Manfred Liebsch et al. · Toxicology in Vitro · 1993 · 99 citations

Pharmacy, Toxicology, Industrial Toxicology +13