Concepedia

Metal-free, visible-light driven C–H ketoalkylation of glycine derivatives and peptides

Zi-Hang Yuan, Mingyu Yang, Minghua Wang, Xin‐Hua Duan, Li‐Na Guo

Green Chemistry · 2021 · 49 citations · 43 references

DOI

Concepts

Abstract

A metal free, visible-light driven C–H ketoalkylation of glycine derivatives and peptides with cycloalkyl hydroperoxides is presented. This protocol provides diverse unnatural amino acids bearing a distal carbonyl group in moderate to good yields.

References

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Gen Zhang, Yaohu Zhang, Rui Wang · Angewandte Chemie International Edition · 2011 · 282 citations · Full text

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