Concepedia

Berberine ameliorates erectile dysfunction in rats with streptozotocin‐induced diabetes mellitus through the attenuation of apoptosis by inhibiting the SPHK1/S1P/S1PR2 and MAPK pathways

Kang Liu, Taotao Sun, Yang Luan, Yinwei Chen, Jingyu Song, Le Ling, Penghui Yuan, Rui Li, Kai Cui, Yajun Ruan,

Andrology · 2021 · 42 citations · 39 references

DOI

Abstract

Berberine ameliorated erectile dysfunction in rats with diabetes mellitus, possibly by improving endothelial function and inhibiting apoptosis and fibrosis by suppressing the sphingosine kinase 1/sphingosine-1-phosphate/S1PR2 and mitogen-activated protein kinase pathways.

References

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