A–DA′D–A fused-ring small molecule-based nanoparticles for combined photothermal and photodynamic therapy of cancer

Bing Lü, Zhecheng Zhang, Danni Jin, Xiaolei Yuan, Jin Wang, Yue Ding, Yang Wang, Yong Yao

Chemical Communications · 2021 · 37 citations · 27 references

Concepts

Abstract

New nanoparticles (Y6 NPs) based on the A-DA'D-A fused-ring conjugated small molecule Y6 have been prepared for the combined photothermal and photodynamic therapy of cancer. Y6 NPs show excellent light absorption from 300 to 900 nm, a good photothermal conversion efficiency of 57% and reactive oxygen species generation capability. The high photothermal conversion ability and superior photodynamic activity of Y6 NPs endow them with great potential for cancer therapy.

References

27