Annals of Clinical Biochemistry International Journal of Laboratory Medicine · 2021 · 291 citations · 2 references
Natural SciencesBiostatisticsStatisticsData TransformationLog NormalizationLog TransformationLog-normal ModelReference Interval DeterminationReference Interval EstablishmentT-test
The log transformation is often used to reduce skewness of a measurement variable. If, after transformation, the distribution is symmetric, then the Welch t-test might be used to compare groups. If, also, the distribution becomes close to normal, then a reference interval might be determined.
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