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Publication | Open Access

The Intraocular Pressure Lowering Effect of a Dual Kinase Inhibitor (ITRI-E-(S)4046) in Ocular Hypertensive Animal Models

DOIFull Paper Access

10

Citations

14

References

2021

Year

Yi‐Hsun Chen, Wan-Ying Lin, Yu Chuan Huang, Wan Yu Ho, Chih‐Wei Fu, Chia-Mu Tu, Chrong-Shiong Hwang, Chiu-Lien Hung, Ming-Chun Lin, Felice Cheng,
Investigative Ophthalmology & Visual Science

Abstract

ITRI-E-(S)4046 is a novel type of highly specific ROCK1/2 and MYLK4 inhibitor that can reduce IOP in normotensive and hypertensive animal models. It has the potential to become an effective and well-tolerated treatment for glaucoma.

References

YearCitations

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