Rapamycin-loaded Poly(lactic-co-glycolic) acid nanoparticles: Preparation, characterization, and in vitro toxicity study for potential intra-articular injection

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee

Sharon L. Kolasinski, Tuhina Neogi, Marc C. Hochberg et al. · Arthritis & Rheumatology · 2020 · 1.9K citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Tor, a Phosphatidylinositol Kinase Homologue, Controls Autophagy in Yeast

Takeshi Noda, Yoshinori Ohsumi · Journal of Biological Chemistry · 1998 · 1.3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis

Timothy E. McAlindon, Michael P. LaValley, William F. Harvey et al. · JAMA · 2017 · 830 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Autophagy activation by rapamycin reduces severity of experimental osteoarthritis

B. Caramés, Akihiko Hasegawa, Noboru Taniguchi et al. · Annals of the Rheumatic Diseases · 2011 · 466 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Inhibition of PI3K/AKT/mTOR signaling pathway promotes autophagy of articular chondrocytes and attenuates inflammatory response in rats with osteoarthritis

Jianfeng Xue, Zhongmin Shi, Jian Zou et al. · Biomedicine & Pharmacotherapy · 2017 · 423 citations

Life Sciences, Cell Biology, Orthopedic Surgery +14