Frontiers in Public Health · 2021 · 16 citations · 29 references
ComputingComputer ScienceNeuroscienceDementiaMachine LearningNeurodegenerationAlzheimer DiseaseDeep LearningDementia PreventionNeurodegenerative DiseasesNeurodegenerative DisordersPredictive ModelingAlzheimer's Disease PreventionAmyloid Beta PeptidesConvolutionDisease PrognosticationEarly Detection Of DementiaEarly Onset Alzheimer DiseaseLogistic RegressionMachine Learning Prediction Models
Alzheimer's Disease (AD) is a neurodegenerative irreversible brain disorder that gradually wipes out the memory, thinking skills and eventually the ability to carry out day-to-day tasks. The amount of AD patients is rapidly increasing due to several lifestyle changes that affect biological functions. Detection of AD at its early stages helps in the treatment of patients. In this paper, a predictive and preventive model that uses biomarkers such as the amyloid-beta protein is proposed to detect, predict, and prevent AD onset. A Convolution Neural Network (CNN) based model is developed to predict AD at its early stages. The results obtained proved that the proposed model outperforms the traditional Machine Learning (ML) algorithms such as Logistic Regression, Support Vector Machine, Decision Tree Classifier, and K Nearest Neighbor algorithms.
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Forecasting the global burden of Alzheimer's disease
Ron Brookmeyer, Elizabeth M. Johnson, Kathryn Ziegler‐Graham et al. · Alzheimer s & Dementia · 2007 · 3.4K citations
Medicine, Geriatric Medicine, Population Health Sciences +17
Analysis of Dimensionality Reduction Techniques on Big Data
Thippa Reddy Gadekallu, Praveen Kumar Reddy Maddikunta, Kuruva Lakshmanna et al. · IEEE Access · 2020 · 869 citations · Full text