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Design, synthesis and biological evaluation of cinnamamide-quinazoline derivatives as potential EGFR inhibitors to reverse T790M mutation

Medicinal ChemistryHealth SciencesPotential Egfr InhibitorsMedicineRational Drug DesignCinnamamide-quinazoline DerivativesPharmacotherapyT790m MutationAnti-cancer AgentDrug DevelopmentPharmacologyRadiation OncologyNovel TherapyDrug DiscoveryDrug Resistance