Concepedia

Cephaeline is an inductor of histone H3 acetylation and inhibitor of mucoepidermoid carcinoma cancer stem cells

Luan César Silva, Gabriell Bonifácio Borgato, Vivian Petersen Wagner, Manoela Domingues Martins, Guilherme Z. Rocha, Márcio Ajudarte Lopes, Alan Roger Santos‐Silva, Gilberto de Castro, Luiz Paulo Kowalski, Jacques E. Nör,

Journal of Oral Pathology and Medicine · 2021 · 26 citations · 24 references

DOIFull text

Open access

Abstract

Cephaeline has shown anti-cancer properties in all MEC cell lines tested by regulating tumor cells' viability, migration, proliferation, and disrupting the ability of cancer cells to generate tumorspheres.

References

24

Guidelines for accurate EC50/IC50 estimation

Jeanne L. Sebaugh · Pharmaceutical Statistics · 2010 · 877 citations

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Upregulation and Nuclear Recruitment of HDAC1 in Hormone Refractory Prostate Cancer

Kalipso Halkidou, Luke Gaughan, Susan Cook et al. · The Prostate · 2004 · 502 citations

Increased expression of histone deacetylase 2 is found in human gastric cancer

Jaehwi Song, Ji Heon Noh, Jong‐Heun Lee et al. · Apmis · 2005 · 341 citations

Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry

Shu Yang, Miao Xu, Emily M. Lee et al. · Cell Discovery · 2018 · 185 citations · Full text

Phase II trial of taxol in salivary gland malignancies (E1394): A trial of the Eastern Cooperative Oncology Group

Jill Gilbert, Yi Li, Harlan A. Pinto et al. · Head & Neck · 2006 · 177 citations